The Detroit Tigers will look to show their highway fortunes round after they battle the Houston Astros within the third and last sport of their sequence on Wednesday. Houston earned an 8-5 win on Monday, and a come-from behind 6-4 victory on Tuesday. The Tigers (18-12), who lead the American League Central, are simply 5-9 on the highway in 2025. The Astros (16-13), who’ve a plus-16 run differential, are 11-6 on their dwelling subject this season.
First pitch from Daikin Park in Houston is ready for two:10 p.m. ET. The Astros have received eight of the final 12 conferences in opposition to the Tigers. Houston is a -125 favourite on the cash line (danger $125 to win $100) within the newest Astros vs. Tigers odds from Fanduel Sportsbook, whereas the entire variety of runs Vegas thinks can be scored, or the over/underneath, is 8.5. Earlier than making any Tigers vs. Astros picks, make sure you see the MLB predictions and betting advice from SportsLine’s proven computer model.
The SportsLine Projection Mannequin simulates each MLB sport 10,000 instances. It enters Week 6 of the 2025 MLB season on a 17-11 run on top-rated MLB betting picks (+276). Anyone following at sportsbooks and on betting apps may have seen sturdy returns.
Now, the mannequin has set its sights on Tigers vs. Astros and simply locked in its picks and MLB predictions. You can head to SportsLine now to see the model’s picks. Listed below are a number of MLB odds and betting traces for Astros vs. Tigers:
- Tigers vs. Astros cash line: Detroit +105, Houston -125 at FanDuel Sportsbook
- Tigers vs. Astros over/underneath: 8.5 runs
- Tigers vs. Astros run line: Houston -1.5 (+163)
- DET: The underneath is 4-1-1 within the Tigers’ final six video games
- HOU: The underneath is 7-3 within the Astros’ final 10 video games
- Tigers vs. Astros picks: See picks at SportsLine
- Tigers vs. Astros streaming: FuboTV (Strive free of charge)
Why the Astros can cowl
Houston is predicted to both name up A.J. Blubaugh for a spot begin. In 4 begins at AAA Sugar Land of the Pacific Coast League, he’s 2-2 with a 3.86 ERA. In 12 begins at Sugar Land in 2024, he was 12-4 with a 3.83 ERA. In 4 minor league seasons, he has gone 22-10 with a 4.02 ERA in 65 video games, together with 44 begins.
Left fielder Jose Altuve is amongst Houston’s prime hitters. In 28 video games this season, he’s batting .272 with two doubles, 4 homers and 12 RBI. He had two hits, one homer and three RBI in Monday’s sequence opener. He has all the time hit Tigers pitching effectively. In 43 profession video games in opposition to Detroit, he’s batting .306 with seven doubles, one triple, eight homers and 21 RBI. See which team to back at SportsLine.
Why the Tigers can cowl
Detroit is predicted to counter with right-hander Jackson Jobe (2-0, 2.70 ERA). In his final outing, a 7-3 win over the Kansas City Royals, he picked up the victory, pitching 5 innings and permitting 5 hits, one earned run and two walks, whereas putting out 5. He additionally earned a win in a 4-0 triumph at Minnesota on April 12. In that sport, he went six innings, permitting simply two hits and one stroll, whereas putting out two.
Second baseman Gleyber Torres is coming off a strong efficiency in Tuesday’s loss to the Astros. He went 3-for-5 with a homer and three RBI. In 18 video games this season, he’s batting .292 with two doubles, three homers and 14 RBI. In 40 profession video games in opposition to Houston, he’s hitting .257 with 5 doubles, seven homers and 20 RBI. See which team to back at SportsLine.
The best way to make Tigers vs. Astros picks
SportsLine’s mannequin is leaning Over on the entire, projecting 9.4 mixed runs, and it says one facet of the cash line has all the worth. You can head to SportsLine to see the model’s MLB picks.
So who wins Astros vs. Tigers, and which facet has all the worth? Visit SportsLine now to see which side you need to jump on, all from the model that has crushed its MLB picks, and discover out.
